CONFIGURATION CHANGE OF SURFACE SIALIC ACID DURING MITOSIS
نویسندگان
چکیده
منابع مشابه
Configuration Change of Surface Sialic Acid during Mitosis
Changes in the metabolic state of a cell that permit (and perhaps trigger) mitosis are suggested from a variety of observations (see general discussions of the premitotic state: references 5, 7, 13). A list of such premonitory indications of mitosis should probably include increase in nuclear volume, loss of cellular water, cortical and endoplasmic viscosity changes partly or wholly related to ...
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The surface distribution of concanavalin A (Con A) bound to cell membrane receptors varies dramatically as a function of mitotic phase. The lectin is distributed diffusely on cells labeled and observed between mid-prophase and early anaphase, whereas cells observed in late anaphase or telophase demonstrate a marked accumulation of Con A-receptor complexes over the developing cleavage furrow (Be...
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The stereochemistry of the ketosidic bond of sialic acid has been elucidated by a study of the two anomeric methyl ketosides. Isomer I was prepared by Koenig.+Knorr synthesis, and isomer II by direct methylation with methanol and an acid catalyst. These two anomeric configurations were established by conversion with periodate-borohydride to III and IV, respectively, followed by lactonization of...
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Using single cell-imaging methods we have found that the volume of adherent cells grown in culture decreases as the cells rounds when it enters mitosis. A minimal volume is reached at metaphase. Rapid volume recovery initiates before abscission as cells make the transition from metaphase to cytokinesis. These volume changes are simultaneous with the rapid surface area decrease and recovery obse...
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5-HIAA in the caudate nucleus (Alzheimer, 3.2 f 1.7; control, 5.2k2.3; P< 0.01), HVA in the caudate nucleus (Alzheimer, 13.5k5.0; control, 24.6k7.3; P<O.OI) and HVA in putamen (Alzheimer, 2.3 k0.9; control, 4.7k2.6; P<0.002). The highest CSF concentration of HVA is in the lateral ventricles, which are adjacent to the dopamine-rich caudate nucleus. Therefore, it seems likely that the CSF deficit...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1967
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.33.1.197